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The Moderna Therapeutics, Inc. patent solves the following problem:
Cancer is a disease characterized by uncontrolled cell division and growth in the body. In the United States, roughly a third of all women and half of all men will experience cancer in their lifetime. Polypeptides involved in every aspect of the disease, including cancer cell biology (carcinogenesis, cell cycle repression, DNA repair and angiogenesis), treatment (immunotherapy, hormone manipulation, enzymatic inhibition), diagnosis and determination of cancer types (molecules points for the breast, prostate, colon and cervical cancer for example). Many of the unfavorable outcome with standard treatments like chemotherapy and radiotherapy being used, genetic therapy to control the disease related peptides provides a more targeted approach to disease diagnosis, treatment and management.
Our analysis of this patent is as follows:
Moderna Therapeutics, Inc.’s patent US 9216205 B2 deals with Modified polynucleotides encoding granulysin.
The invention relates to compositions and methods for the preparation, performance and therapeutic use in oncology-related polynucleotides, Oncology-related primary transcripts and oncology-related molecular mmRNA.
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